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Lithin SR

Unit Price:

Tablet (Sustained Release)

🧬 Lithium Carbonate 🏢 Incepta Pharmaceuticals Ltd.
Generic Name Lithium Carbonate
Strength 400 mg
Manufacturer Incepta Pharmaceuticals Ltd.
Unit Price Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00) Strip Price: ৳ 50.00

🔹 নির্দেশনা

Lithin SR is indicated in treatment and prophylaxis of mania, bipolar disorder and recurrent depression.

🔹 ফার্মাকোলজি

Although lithium has been used for over 50 years in treatment of bipolar disorder, the mechanism of action is still unknown.  Lithium's therapeutic action may be due to a number of effects, ranging from inhibition of enzymes such as glycogen synthase kinase 3, inositol phosphatases, or modulation of glutamate receptors. Lithium Carbonate alters intraneuronal metabolism of catecholamines and sodium transport in neurons and muscle cells.

🔹 মাত্রা ও ব্যবহারবিধি

Adult and child over 12 years: initially 1 gm to 1.5 gm daily; prophylaxis, initially 300-400 mg daily. Should be taken with food.

🔹 মিথস্ক্রিয়া

Caution should be used when lithium and diuretics are used concomitantly because diuretic-induced sodium loss may reduce the renal clearance of lithium and increase serum lithium levels with risk of lithium toxicity. Lithin SR levels should be closely monitored when patients initiate or discontinue NSAID use. Indomethacin and piroxicam have been reported to increase significantly steady-state plasma lithium concentrations. Concurrent use of metronidazole with lithium may provoke lithium toxicity due to reduced renal clearance. There is evidence that ACE inhibitors, such as enalapril and captopril, may substantially increase steady-state plasma lithium levels, sometimes resulting in lithium toxicity. Concurrent use of calcium channel blocking agents with lithium may increase the risk of neurotoxicity in the form of ataxia, tremors, nausea, vomiting, diarrhoea and/or tinnitus. The concomitant administration of lithium with selective serotonin reuptake inhibitors should be undertaken with caution as Lithin SR has been reported to result in symptoms such as diarrhea, confusion, tremor, dizziness and agitation. The following drugs can lower serum lithium concentrations by increasing urinary lithium excretion: acetazolamide, urea, xanthine preparations and alkalinizing agents such as sodium bicarbonate. The following have also been shown to interact with lithium: methyldopa, phenytoin and carbamazepine.

🔹 প্রতিনির্দেশনা

Renal insufficiency, cardiovascular insufficiency, Addison's disease and untreated hypothyroidism are all contraindications to lithium therapy.

🔹 পার্শ্ব প্রতিক্রিয়া

Tiredness, loss of appetite, nausea, vomiting, diarrhoea, hands shaking, memory problems, increased thirst and consequently passing urine more often by day, and perhaps also by night.

🔹 গর্ভাবস্থায় ও স্তন্যদানকালে

Pregnancy Category D. An increased incidence of cardiovascular abnormality has been noted in infants of women given lithium during the first 3 months of pregnancy, such use should be avoided unless essential. Breast feeding is not advised unless the benefits of lithium use outweigh the advantages.

🔹 সতর্কতা

Decreased tolerance to lithium has been reported to ensue from protracted sweating or diarrhoea and, if such occur, supplemental fluid and salt should be administered under careful medical supervision and lithium intake reduced or suspended until the condition is resolved.

🔹 সংরক্ষণ

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

🔍 লোকজন আরও খুঁজছেন

Unit Price: Unit Price: এর কাজ কি Unit Price: খাওয়ার নিয়ম Unit Price: এর দাম কত Unit Price: এর পার্শ্বপ্রতিক্রিয়া Unit Price: কিসের ওষুধ Unit Price: এর ডোজ Unit Price: সম্পর্কে বিস্তারিত Lithium Carbonate Incepta Pharmaceuticals Ltd. বাংলাদেশের ঔষধ Unit Price: 400 mg

💡 Frequently Asked Questions

Lithin SR is indicated in treatment and prophylaxis of mania, bipolar disorder and recurrent depression.
Adult and child over 12 years: initially 1 gm to 1.5 gm daily; prophylaxis, initially 300-400 mg daily. Should be taken with food.
Tiredness, loss of appetite, nausea, vomiting, diarrhoea, hands shaking, memory problems, increased thirst and consequently passing urine more often by day, and perhaps also by night.

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