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Arpolax

Arpolax

Tablet

🧬 Citalopram Hydrobromide 🏢 Incepta Pharmaceuticals Ltd.
Generic Name Citalopram Hydrobromide
Strength 20 mg
Manufacturer Incepta Pharmaceuticals Ltd.
Unit Price Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00) Strip Price: ৳ 80.00

🔹 Indications

Arpolax is indicated for-
  • Depressive illness
  • Panic disorder

🔹 Pharmacology

Citalopram is bicyclic phthalane derivative and a selective serotonin re-uptake inhibitor, with little or no effect on noradrenaline, dopamine and GABA re-uptake. The inhibitory activity explains the antidepressant property of citalopram. It has no or very low affinity for 5-HT1AA, 5-HT2A, D1 and Dreceptors, α1, α2, β-adrenergic, histamine H1, muscarinic, cholinergic, benzodiazepine and opioid receptors.

🔹 Dosage & Administration

Depressive illness:
  • Adult: 20 mg daily as a single dose in the morning or evening increased if necessary to max. 60 mg daily
  • Elderly: Max 40 mg daily.
  • Child: Not recommended.
Panic disorder:
  • Adult: Initially 10 mg daily increased to 20 mg after 7 days, usual dose 20-30 mg daily; max. 60 mg daily
  • Elderly: Max 40 mg daily
  • Child: Not recommended.

🔹 Interaction

Citapram should not be taken cocurrently with MAOIs, Serotonin agonists, Neuroleptics, Cimetidine, Alcohol, Ketoconazole, Itraconazole, Macrolide antibiotics.

🔹 Contraindications

Citalopram should not be used if the patient enters a manic phase.

🔹 Side Effects

Palpitation, postural hypotension, coughing, yawning, confusion, impaired concentration, amnesia, migraine, taste disturbance, increased salivation, rhinitis, tinnitus, micturition disorders.

🔹 Pregnancy & Lactation

Pregnancy: There are on adequate and well-controlled studies in pregnant women; therefore, Citalopram should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Lactation: Citalopram is excreted in human breast milk. So, the decision whether to continue or discontinue either nursing or Citalopram therapy should take into account the risks of Citalopram exposure for the infants and the benefits of Citalopram treatment for the mother.

🔹 Precautions & Warnings

Arpolax should be used with caution in patients with epilepsy, concurrent electroconvulsive therapy, history of mania, cardiac disease, diabetes mellitus, angle-closure glaucoma, history of bleeding disorders, hepatic and renal impairment, pregnancy and breast feeding.

🔹 Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

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💡 Frequently Asked Questions

Arpolax is indicated for- Depressive illness Panic disorder
Depressive illness: Adult: 20 mg daily as a single dose in the morning or evening increased if necessary to max. 60 mg daily Elderly: Max 40 mg daily. Child: Not recommended. Panic disorder: Adult: Initially 10 mg daily increased to 20 m...
Palpitation, postural hypotension, coughing, yawning, confusion, impaired concentration, amnesia, migraine, taste disturbance, increased salivation, rhinitis, tinnitus, micturition disorders.

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